Background: Memorizing the Quran is an education continuing from the early periods of Islamic education until today. Although this education started in the past to protect the Quran, nowadays, it is continuing as a tradition. Aims and Objectives: The main purpose of this study is to investigate the effects of memorizing the Quran on certain cognitive functions of individuals. Materials and Methods: The scope of the study is limited to 18 female and 15 male students who have been studying in the 5th, 6th, and 7th grades of Anatolian Imam Preacher Secondary Schools in different districts of İstanbul. After Demographic Information Questionnaire was used, California Verbal Learning Test children’s version, Wechsler Memory Scale revised visual reproduction subtest, Trail Making Test, and Verbal Fluency Test were applied twice to collect data about individuals before and after memorization training. Results: Findings demonstrated that there is a statistically significant difference
in verbal learning, visual learning, attention speed, and phonemic and semantic fluency before and after memorization training. Conclusion: In conclusion, memorizing the Quran has positive impacts on verbal and visual memory, attention processes, and lexical and semantic fluency of individuals. It is important with regard to eliminate emptiness in the literature. In future studies, it can be investigated the effects of textual memorization in a foreign language on brain structures and connections.

Amaç: Alzheimer Hastalığı, ilerleyici bellek bozukluğuyla karakterize bir nörodejeneraitf hastalıktır. Fakat, otobiyografik belleğin bir alt grubu olarak kabul edilen ve emosyonel içeriği olan flaşbelleğin Alzheimer hastalığında aynı derecede etkilenip etkilenmediği yeterince açık değildir. Yöntem: Bu çalışmada, 29 erken evre Alzheimer hastalığı olan katılımcıların flaşbellek performansı incelenmiş ve sağlıklı genç yetişkinlerle karşılaştırılmıştır. Ek olarak, hasta grubunun sözel bellek performansı Öktem Sözel Bellek Süreçleri Testi kullanılarak ölçülmüştür. Sonuç: Yapılan analizler sonucuda, Alzheimer hastalığı olan grubun sözel bellek kayıt sürecinde anlamlı kayıp bulunmasına ragmen flaşbellek performansları açısından sağlıklı genç yetişkinler ile aralarında anlamlı fark bulunmamıştır. Tartışma: Sonuç olarak, bu çalışma flaşbelleğin özel bir nöral şebekeye sahip olduğu görüşünü destekleyerek, erken evre Alzheimer Hastalığında flaşbellek performansının korunuyor olabileceğini düşündürmektedir.

Transkraniyal Manyetik Uyarım (TMU) dünyada yaygın kullanılan tedavi yöntemlerinden biri değildir. Psikiyatrik tedaviler için ayrılan bütçenin kısıtlılığı yanısıra psikiyatristlerin TMU’ya dair bilgileri ve tutumları da TMU’nun yaygın kullanımını olumsuz etkileyebilir. Bu anket çalışmasında Türkiye’de çalışan psikiyatri asistanları ve uzmanlarının TMU’ya yönelik tutum ve bilgilerinin ölçülmesi amaçlanmıştır. Araştırmacıların geliştirdiği ve hekimlerin sosyodemografik bilgileri, TMU’ya yönelik bilgileri ve tutumlarını ölçen 26 soruluk anket psikiyatri asistan ve uzmanlarının üye olduğu kapalı bir e-posta grubuna yönlendirilmiştir. Örneklem 46 kadın ve 61 erkekten oluşuyordu. TMU’ya dair bilgi sahibi olmak, katılımcıların TMU’yu umut vaat eden bir tedavi yöntemi olarak görmesini, TMU’nun bir tedavi olarak yaygınlaşmasını onaylamayı ve TMU’nun etki mekanizması hakkında daha fazla bilgi sahibi olma isteğini istatistiksel anlamlı olarak etkiliyordu (p=0.006; p=0.019 and p=0.013);ancak, TMU’yu etkili bir tedavi yöntemi olarak kabul etmeyi, TMU’yu hastaları yanıltmaya yönelik bir tedavi olarak görmeyi ve TMU’yu sadece tedaviye dirençli olgularda kullanmayı anlamlı olarak (p=0.060, p=0.065, and p=0.136). Türkiye’den katılımcı hekimlerin çoğunun TMU’ya dair olumlu fikirleri olduğu ve TMU’ya dair daha fazla bilgi sahibi olmak istedikleri gözlemlendi. Bilimsel toplantılarda TMU’ya dair sunumların sayısını arttırmak ve asistanlık eğitimleri sırasında TMU uygulanan kliniklerde rotasyon imkanı sağlamak faydalı olabilir.

Aim: The study's long-term goals, such as determining supratherapeutic ranges according to age distributions
specific to the country, adjusting dosages for additional drugs used by patients in different disease
groups, and providing the opportunity for etiological studies in the light of diagnosis and drug metabolism
perspective, are of great importance in defining the study. Method: Population pharmacokinetics is a
method expressed to evaluate processes such as absorption, distribution, metabolism, and elimination of a
drug from an individual's blood-plasma concentration. In drug pharmacokinetic experiments, generating
data without considering any pharmacokinetic differences among patients prevents the measurement or
observation of variability among individuals in the population as a simple approach. The dose-concentration
relationship is crucial for individualized dose adjustment. Additionally, the impact of other drugs used
by the individual on metabolite levels and the metabolic interactions between drugs play a critical role in
the development of personalized treatments. Population approaches provide a foundation that benefits the
observation of these effects. The variability in drug metabolism among individuals forms one of the fundamental
building blocks of personalized treatment approaches, specifically through Therapeutic Drug Monitoring
(TDM), which plays an important role in determining the therapeutic range of drugs. Materials:
In this study, drug metabolism findings of patients served at NP Istanbul Brain Hospital between 2010 and
2022 were examined within the repository created along with other patient-specific parameters. Results
and Conclusion: The analysis results have been followed up longitudinally, partially demographically,
and retrospectively. Thanks to the repository of NP Istanbul Brain Hospital, population pharmacokinetic
analyses aimed in this study are being conducted for the first time globally and nationally in terms of
scope. The repository has been studied with TDM for individualized treatment methods, and within this
project, it is anticipated to perform phenotyping with the population pharmacokinetic approach.

Aim: Autism spectrum disorder (ASD) is a common neurodevelopmental disorder affecting
multiple levels of social and cognitive skills and causing a significant health‑care burden.
Currently, there is no approved treatment for ASD. Methods: In this study, 10 children with
ASD between the ages 6 and 19 years (M = 12.3, standard deviation = 3.94) were recruited.
Repetitive transcranial magnetic stimulation (rTMS) was applied and symptom severity was
measured before and after treatment using the Childhood Autism Rating Scale (CARS) and
Autistic Behavior Checklist (ABC). All children received sessions of low‑frequency rTMS to the
bilateral prefrontal cortices. Results: The results showed that the children improved according
to both symptom ratings. Specifically, both the relating (z = −2.02, P < 0.05), body and object
use (z = −2.03, P < 0.05) and language (z = −2.21, P < 0.05) subscale scores and the total
score of ABC (z = −2.37, P < 0.05) decreased. Regarding CARS, visual response (z = −2.06,
P < 0.05), verbal communication (z = −2.12, P < 0.05) subscale scores, and the total score (z
= −2.52, P = 0.01) decreased significantly after TMS therapy. Conclusion: Our study was open
label and in terms of sample size should be considered a pilot study. Although the results should
be evaluated cautiously, the findings suggest that rTMS might be a safe and useful tool for
improving deficits related to ASD in children.