JNBS
Üsküdar Üniversitesi

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Case Report

SARS‑CoV‑2 Infection‑Related Acute Parkinsonism and Encephalitis: Is There a Clinicoradiological Correlation?

Turkish Title : SARS‑CoV‑2 Infection‑Related Acute Parkinsonism and Encephalitis: Is There a Clinicoradiological Correlation?

Vikash Agarwal,Dolly Mushahary,Praveen Chander,K. Venkatraman,K. Lakshminarayanan,Sathish Kumar V.,Dinesh Nayak S.
JNBS, 2022, 9(2), p:77-81

DOI : 10.4103/jnbs.jnbs_45_21

COVID‑19 infection can cause neurological manifestations as early and late complications (chronic
COVID syndrome). These include headache, dizziness, confusion, acute cerebrovascular problems,
ataxia, and seizures. COVID‑19‑related encephalopathy, encephalitis, and parkinsonism have been
reported earlier; however, the possible links and pathophysiological mechanisms are unclear. In this
report, we report a series of patients (n = 5) presenting with acute severe neurological syndromes
such as parkinsonism, focal status epilepticus, or acute ataxia as a part of long‑hauler COVID‑19
infection. We categorized the clinico-radiological and electroencephalographic features in our cases to
understand the clinical patterns in SARS-CoV-2 related brain cortex involvement. This might help
in future for better clinical categorization for these COVID‑19‑related neurological manifestations.

COVID‑19 infection can cause neurological manifestations as early and late complications (chronic
COVID syndrome). These include headache, dizziness, confusion, acute cerebrovascular problems,
ataxia, and seizures. COVID‑19‑related encephalopathy, encephalitis, and parkinsonism have been
reported earlier; however, the possible links and pathophysiological mechanisms are unclear. In this
report, we report a series of patients (n = 5) presenting with acute severe neurological syndromes
such as parkinsonism, focal status epilepticus, or acute ataxia as a part of long‑hauler COVID‑19
infection. We categorized the clinico-radiological and electroencephalographic features in our cases to
understand the clinical patterns in SARS-CoV-2 related brain cortex involvement. This might help
in future for better clinical categorization for these COVID‑19‑related neurological manifestations.


ISSN (Print) 2149-1909
ISSN (Online) 2148-4325

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