In this study, it was aimed to investigate the effects of highbush cranberry ( Viburnum opulus , GILA) fruit extract on blood glucose levels and kidney tissue homogenates of diabetes-modeled rats by injection of Streptozotocin (STZ). Blood glucose levels of rats were measured in tail blood using a glucose meter. Glucose determination was done 48 hours after STZ injection. For this, 32 Wistar albino rats were employed. The rats were divided into 4 groups; Control, STZ, STZ+GILA, and GILA with containing 8 animals each. After 12 weeks, they were sacrificed. During the study periods, blood glucose levels were measured periodically and kidney tissue parameters were measured in their homogenates after sacrificing the rats. The measured parameters were Glutathion (GSH), Malondialdehyde (MDA), and Total Antioxidant Status (TAS). The results obtained from the study were analyzed by using SPSS for Windows software, and p<0.05 was assigned as statistically significant value. The findings of the study showed that GILA consumption could help diabetic people to prevent possible nephropathy due to its potent antioxidant features. 

In this review, the biological structure of garlic, its active ingredients, especially allicin and its way
of antimicrobial effects on cells evaluated and also the toxic possibility of allicin on diverse cells was
investigated. Various academic papers have been found in reliable literature. It is stated that garlic
includes lots of phytoconstituents with activities against cells. The toxic action of allicin on different
cell lines such as bacteria kinds such as Gram-positive (Staphylococcus aureus, Bacillus subtilis,
Streptococcus pneumoniae) and Gram-negative bacteria (Klebsiella pneumoniae, Helicobacter pylori,
Escherichia coli, Pseudomonas aeruginosa) for all that fungi like Candida albicans and parasites,
virus, glioma and human neuroblastoma cell lines and also oral tongue squamous cell carcinoma,
cancer cell lines which are characterized as malignant (leukemia, colon, gastric, and breast cell
lines) cancer. It has been revealed that, on those cells, allicin has also been demonstrated toxicity
mechanisms on cells like canceling deed of nitric oxide synthase, the peroxidation of lipids, nuclear
factor, kappa B, arranging cell period, modulating the activity of redox precision proteins and
influence cellular signaling.